Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470751 | 0.88 | SMN1; SMN2 (0.42) | GPR174ARALDH1A1GAAMAPT | |
| SCHEMBL5695821 | 0.85 | RAB9A (0.43) | ALDH1A1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL1471423 | 0.82 | ALDH1A1 (0.47) | GPR174ALDH1A1GAAMAPTHTT | |
| SCHEMBL1470893 | 0.73 | SMN1; SMN2 (0.40) | GPR174ARALDH1A1GAAMAPT | |
| SCHEMBL1470736 | 0.73 | NPC1 (0.41) | ALDH1A1MAPTHTTLMNARECQL | |
| SCHEMBL12684711 | 0.73 | APP (0.57) | ALDH1A1MAPTHTTLMNANPSR1 | |
| SCHEMBL1470908 | 0.72 | HTR1A (0.42) | ALDH1A1GAAHTTLMNARECQL | |
| SCHEMBL1471446 | 0.72 | HDAC1 (0.41) | ALDH1A1HTTLMNARECQLTDP1 | |
| SCHEMBL12497081 | 0.72 | APP (0.58) | ALDH1A1MAPTHTTLMNANPSR1 | |
| SCHEMBL1471442 | 0.71 | HTR1A (0.52) | GAAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660472-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021525-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-10 | — | — | WO | disclosed |