Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666594 | 0.86 | USP30 (0.51) | KDM4EALDH1A1MAPTTACR1EPHX2 | |
| SCHEMBL5119863 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTTACR1MRGPRX1 | |
| SCHEMBL5993452 | 0.81 | SLC6A2 (0.49) | KDM4EALDH1A1MAPTCYP2C9PGR | |
| SCHEMBL16269040 | 0.80 | SCN9A (0.51) | KDM4ETACR1EPHX2CYP2C9SIGMAR1 | |
| SCHEMBL5758822 | 0.80 | SCN9A (0.51) | KDM4ETACR1EPHX2CYP2C9SIGMAR1 | |
| SCHEMBL3652853 | 0.79 | EPHX2 (0.57) | EPHX2CYP2C9 | |
| SCHEMBL4476067 | 0.77 | SIGMAR1 (0.53) | KDM4EALDH1A1TACR1MRGPRX1EPHX2 | |
| SCHEMBL4480453 | 0.77 | SIGMAR1 (0.53) | KDM4EALDH1A1TACR1MRGPRX1EPHX2 | |
| SCHEMBL19970345 | 0.77 | SIGMAR1 (0.53) | KDM4EALDH1A1TACR1MRGPRX1EPHX2 | |
| SCHEMBL16268490 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1MAPTTACR1MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660065-A2 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005020976-A2 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |