Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.71 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.71 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.62 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | TNKS | O95271 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.61 |
| ▸ | GABRP | O00591 | 2/20 | 0.61 |
| ▸ | GABRD | O14764 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24227286 | 0.82 | PLA2G2A (0.97) | PLA2G2APLA2G4APLA2G10ABCG2TNKS | |
| SCHEMBL8371962 | 0.81 | ABCG2 (0.69) | PLA2G2APLA2G4APLA2G10ABCG2CYP1A1 | |
| SCHEMBL12182010 | 0.80 | CASP3 (0.51) | CYP3A4HPGDNPC1RAB9ACA12 | |
| Flavone SCHEMBL28142695 | 0.79 | TNKS (0.90) | PLA2G2APLA2G4APLA2G10ABCG2CYP1A1 | |
| SCHEMBL13979514 | 0.79 | MCL1 (0.47) | CYP1A2HPGDNPC1RAB9ACA12 | |
| SCHEMBL25465791 | 0.78 | MAOB (0.49) | PLA2G2APLA2G4APLA2G10ABCG2CYP1A1 | |
| SCHEMBL530293 | 0.78 | HPGD (0.67) | PLA2G2APLA2G4AABCG2CYP1A2MAPK3 | |
| SCHEMBL31061270 | 0.78 | HPGD (0.67) | PLA2G2APLA2G4AABCG2CYP1A2MAPK3 | |
| SCHEMBL23070093 | 0.78 | TNKS (0.93) | PLA2G2APLA2G4APLA2G10ABCG2CYP1A1 | |
| Flavone SCHEMBL15676601 | 0.77 | TNKS (1.00) | PLA2G2APLA2G4APLA2G10ABCG2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870045-B1 | GENE CONTROL | UNIV DUNDEE (GB) | 2006-07-12 | — | — | EP | disclosed |