Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.69 |
| ▸ | AHR | P35869 | 2/20 | 0.69 |
| ▸ | FYN | P06241 | 1/20 | 0.69 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | AR | P10275 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | GABRP | O00591 | 1/20 | 0.60 |
| ▸ | GABRD | O14764 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Naphthoflavone SCHEMBL29357406 | 0.82 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Beta-Naphthoflavone SCHEMBL43538 | 0.82 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Beta-Naphthoflavone SCHEMBL29881204 | 0.82 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| SCHEMBL5696067 | 0.81 | PLA2G2A (0.71) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Flavone SCHEMBL28142695 | 0.79 | TNKS (0.90) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| SCHEMBL530293 | 0.77 | HPGD (0.67) | ABCG2CYP1A2AHRMAPK3CYP3A4 | |
| SCHEMBL31061270 | 0.77 | HPGD (0.67) | ABCG2CYP1A2AHRMAPK3CYP3A4 | |
| Chrysene SCHEMBL29277001 | 0.77 | TNKS (0.79) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Flavone SCHEMBL15676601 | 0.76 | TNKS (1.00) | ABCG2CYP1A1CYP1A2CYP3A4AR | |
| Flavone SCHEMBL18879 | 0.76 | TNKS (1.00) | ABCG2CYP1A1CYP1A2CYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028464-A2 | CDNAS AND PROTEINS BELONGING TO THE BHLH-PAS SUPERFAMILY OF TRANSCRIPTION REGULATORS AND METHODS OF USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-06-10 | — | — | WO | disclosed |