Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 3/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689261 | 0.93 | MAPT (0.56) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL11942807 | 0.85 | MAPT (0.53) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL9577387 | 0.83 | MAPT (0.51) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL20594083 | 0.66 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Adonitol SCHEMBL22572531 | 0.66 | LMNA (0.83) | MAPTLMNAL3MBTL1TDP1CYP2C19 | |
| Mannitol SCHEMBL23066399 | 0.66 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Sorbitol SCHEMBL763 | 0.66 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Xylitol SCHEMBL20594034 | 0.66 | LMNA (0.83) | MAPTLMNAL3MBTL1TDP1CYP2C19 | |
| Adonitol SCHEMBL20594035 | 0.66 | LMNA (0.83) | MAPTLMNAL3MBTL1TDP1CYP2C19 | |
| Mannitol SCHEMBL21837180 | 0.66 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669355-A1 | Aminotetrahydropteridines and processes for manufacture thereof | Vasopharm Biotech GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2006058669-A2 | AMINOTETRAHYDROPTERIDINES AND PROCESSES FOR THE MANUFACTURE THEREOF | VASOPHARM GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |