Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 4/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696169 | 0.93 | MAPT (0.48) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL11942807 | 0.91 | MAPT (0.53) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL9577387 | 0.90 | MAPT (0.51) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL13187369 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL20594083 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL23066399 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL2297640 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL20594082 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Sorbitol SCHEMBL763 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E | |
| Mannitol SCHEMBL2477078 | 0.71 | LMNA (1.00) | MAPTLMNAL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |