Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898216 | 0.88 | GRIN2D (0.59) | HIPK2GRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL10080461 | 0.88 | GRIN2D (0.59) | HIPK2GRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL20718401 | 0.82 | HIPK2 (0.77) | HIPK2PARP1CSNK2A1 | |
| SCHEMBL10148398 | 0.78 | PTPN1 (0.58) | HIPK2GRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL28170198 | 0.76 | PTPN1 (0.59) | GRIN2DGRIN2AGRIN2CPTPN1PARP1 | |
| SCHEMBL10484311 | 0.75 | ALDH1A1 (0.68) | GRIN2DGRIN2AGRIN2CPTPN1PARP1 | |
| SCHEMBL10080474 | 0.74 | GRIN2D (0.53) | HIPK2GRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL2469662 | 0.73 | ALDH1A1 (0.70) | GRIN2DGRIN2AGRIN2CPTPN1PARP1 | |
| SCHEMBL2343264 | 0.72 | GRIN2D (0.61) | GRIN2DGRIN2AGRIN2CPTPN1PARP1 | |
| SCHEMBL19177351 | 0.72 | GRIN2D (0.61) | GRIN2DGRIN2AGRIN2CPTPN1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |