SCHEMBL5696341

SCHEMBL5696341

CC(=O)C=CCC1=C(C)CCCC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.45
RARB P10826 8/20 0.44
RARG P13631 8/20 0.44
RARA P10276 7/20 0.44
RXRA P19793 6/20 0.44
HAO1 Q9UJM8 1/20 0.43
ALDH1A1 P00352 8/20 0.39
MAPT P10636 5/20 0.39
PTGS1 P23219 4/20 0.39
CYP3A4 P08684 4/20 0.39
ALOX15 P16050 3/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 2/20 0.39
RORC P51449 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
MAPK1 P28482 2/20 0.39
HTR2B P41595 2/20 0.39
BLM P54132 2/20 0.39
HIF1A Q16665 2/20 0.39
DRD3 P35462 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2706978 0.88 CYP1A2 (0.56) CYP1A2RARBRARGRARARXRA
SCHEMBL2706976 0.88 CYP1A2 (0.56) CYP1A2RARBRARGRARARXRA
SCHEMBL11452887 0.85 HAO1 (0.44) CYP1A2RARBRARGRARARXRA
SCHEMBL11452886 0.85 HAO1 (0.44) CYP1A2RARBRARGRARARXRA
SCHEMBL11740452 0.84 ALOX15 (0.40) CYP1A2RARBRARGRARARXRA
SCHEMBL26967412 0.84 ALDH1A1 (0.43) CYP1A2RARBRARGRARARXRA
SCHEMBL6942717 0.84 CYP1A2 (0.42) CYP1A2RARBRARGRARARXRA
SCHEMBL10088064 0.82 CYP1A2 (0.41) CYP1A2RARBRARGRARARXRA
SCHEMBL5508599 0.78 ALDH1A1 (0.43) CYP1A2RARBRARGRARARXRA
SCHEMBL9483270 0.78 ALDH1A1 (0.43) CYP1A2RARBRARGRARARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1654246-A1 ACETALS, USE THEREOF AS FRAGRANCES AND METHODS FOR PRODUCTION THEREOF Symrise GmbH & Co. KG (DE) 2006-05-10 EP claimed
WO-2005009984-A1 ACETALS, USE THEREOF AS FRAGRANCES AND METHODS FOR PRODUCTION THEREOF SYMRISE GMBH & CO. KG (DE) 2005-02-03 WO claimed