Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 8/20 | 0.44 |
| ▸ | RARB | P10826 | 8/20 | 0.44 |
| ▸ | RARG | P13631 | 8/20 | 0.44 |
| ▸ | RARA | P10276 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706978 | 1.00 | CYP1A2 (0.56) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL5696341 | 0.88 | CYP1A2 (0.45) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL11452886 | 0.85 | HAO1 (0.44) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL11452887 | 0.85 | HAO1 (0.44) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL6942717 | 0.84 | CYP1A2 (0.42) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL9016198 | 0.82 | CYP1A2 (0.51) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL9016196 | 0.82 | CYP1A2 (0.51) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL10088064 | 0.82 | CYP1A2 (0.41) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL11740452 | 0.81 | ALOX15 (0.40) | CYP1A2HAO1RXRARARBRARG | |
| SCHEMBL5508599 | 0.78 | ALDH1A1 (0.43) | CYP1A2HAO1RXRARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2014-07-10 | — | — | US | disclosed |
| US-8409649-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2013-04-02 | — | — | US | disclosed |
| EP-2139841-B1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2012-05-02 | — | — | EP | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | CYP1A2 3689/4885HAO1 2838/4885RXRA 3085/4885 |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | CYP1A2 3689/4885HAO1 2838/4885RXRA 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.