Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695621 | 0.98 | IMPDH2 (0.43) | IMPDH2IMPDH1PTPN1PTPN2CA9 | |
| SCHEMBL5696365 | 0.96 | IMPDH2 (0.42) | IMPDH2IMPDH1PTPN1PTPN2CA9 | |
| SCHEMBL28274538 | 0.84 | IMPDH2 (0.50) | IMPDH2IMPDH1PTPN1PTPN2CA2 | |
| SCHEMBL4353382 | 0.78 | CA1 (0.53) | CA2CA1KDM4ETSHRHTT | |
| SCHEMBL13074509 | 0.77 | CYP2A6 (0.50) | IMPDH2IMPDH1PTPN1PTPN2CA9 | |
| SCHEMBL1344485 | 0.77 | CYP2A6 (0.54) | IMPDH2IMPDH1PTPN1PTPN2CA9 | |
| SCHEMBL29489119 | 0.77 | CYP2A6 (0.54) | IMPDH2IMPDH1PTPN1PTPN2CA9 | |
| SCHEMBL3027689 | 0.76 | CA12 (0.48) | IMPDH2IMPDH1CA9PTPN11CA2 | |
| SCHEMBL2635720 | 0.76 | CA12 (0.48) | IMPDH2IMPDH1CA9PTPN11CA2 | |
| SCHEMBL29489123 | 0.75 | CYP2A6 (0.52) | IMPDH2IMPDH1PTPN1PTPN2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1652837-A1 | AMINOCARBONYL NAPHTHOL DERIVATIVE, CYANONAPHTHOL DERIVATIVE, AND METHOD FOR PRODUCING THEM | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | HCCS, CYP8B1, NCAPD3 | IMPDH2 697/4885IMPDH1 845/4885PTPN1 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.