Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149126 | 0.83 | CA1 (0.64) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL29489128 | 0.83 | CA1 (0.64) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL5695621 | 0.79 | IMPDH2 (0.43) | CA1CA2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL769641 | 0.78 | CA1 (0.59) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL31251446 | 0.78 | CA1 (0.59) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL9804790 | 0.78 | CA1 (0.59) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL5696365 | 0.78 | IMPDH2 (0.42) | CA1CA2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL5696368 | 0.78 | IMPDH2 (0.42) | CA1CA2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL691452 | 0.77 | TRPM4 (0.41) | CA1CA2KDM4EALDH1A1GAA | |
| SCHEMBL7765659 | 0.77 | SNCA (0.43) | CA2ESR2MEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-9045440-B2 | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FerroKin BioScience, Inc. (US) | 2013-02-28 | — | — | US | disclosed |
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| EP-1380577-B1 | Thiazoline acid derivatives | UNIV FLORIDA (US) | 2009-11-18 | — | — | EP | disclosed |
| EP-2096112-A2 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-7384947-B2 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders | BAYER HEALTHCARE LLC (US) | 2008-06-10 | — | — | US | disclosed |
| US-7384947-B2 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders | BAYER HEALTHCARE LLC (US) | 2008-06-10 | — | — | US | disclosed |
| US-7384947-B2 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders | BAYER HEALTHCARE LLC (US) | 2008-06-10 | — | — | US | disclosed |
| US-20060287387-A1 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-12-21 | — | — | US | disclosed |
| EP-1652837-A1 | AMINOCARBONYL NAPHTHOL DERIVATIVE, CYANONAPHTHOL DERIVATIVE, AND METHOD FOR PRODUCING THEM | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20050165042-A1 | Fused tricyclic heterocycles useful for treating hyper-proliferative disoroders | BAYER HEALTHCARE LLC | 2005-07-28 | — | — | US | disclosed |
| CN-1639146-A | Fused tricyclic heterocycles useful for the treatment of hyperproliferative diseases | BAYER PHARMACEUTICALS CORP (US) | 2005-07-13 | — | — | CN | disclosed |
| EP-1478639-A1 | FUSED TRICYCLIC HETEROCYCLES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | Bayer Pharmaceuticals Corporation (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1380577-A1 | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003072566-A1 | FUSED TRICYCLIC HETEROCYCLES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-09-04 | — | — | WO | disclosed |
| US-5840739-A | Thiazoline acid derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0351732-B1 | Polyester composition | TORAY INDUSTRIES (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5110849-A | Moldability at low temperature, melt processability, nonhydrolyzing | TORAY INDUSTRIES, INC. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0351732-A2 | Polyester composition | TORAY INDUSTRIES, INC. (JP) | 1990-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, FTH1 | CA1 2683/4885CA2 2273/4885KDM4E 3390/4885 |
| US-20060287387-A1 | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders | MKI67, CCNA2, CDK4 | CA1 4826/4885CA2 4243/4885KDM4E 3497/4885 |
| US-20050165042-A1 | Fused tricyclic heterocycles useful for treating hyper-proliferative disoroders | MKI67, CCNI, PCNA | CA1 4657/4885CA2 3655/4885KDM4E 3721/4885 |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, FTH1 | CA1 2683/4885CA2 2273/4885KDM4E 3390/4885 |
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | SLC40A1, SLC39A14, HAMP | CA1 2847/4885CA2 2168/4885KDM4E 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.