SCHEMBL5696567

SCHEMBL5696567

CCOC(=O)NC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
HTT P42858 1/20 0.57
NCOA1 Q15788 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
MMP8 P22894 1/20 0.51
CCR3 P51677 1/20 0.51
SOAT1 P35610 1/20 0.49
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889278 0.89 ALDH1A1 (0.52) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL9322212 0.87 CYP3A4 (0.53) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL10359105 0.84 RIPK1 (0.57) HTTSMN1; SMN2MMP8
SCHEMBL10359104 0.84 RIPK1 (0.57) HTTSMN1; SMN2MMP8
SCHEMBL13495005 0.84 RIPK1 (0.57) HTTSMN1; SMN2MMP8
SCHEMBL8136221 0.83 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2MMP8
Hydrochloric Acid SCHEMBL27396293 0.82 SMN1; SMN2 (0.51) ALDH1A1SMN1; SMN2MMP8
SCHEMBL11745735 0.81 NPC1 (0.65) SMN1; SMN2MMP8
SCHEMBL21950095 0.81 NPC1 (0.65) SMN1; SMN2MMP8
SCHEMBL22457805 0.81 PTPRA (0.47) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1118644-B1 Hot melt printing ink SIEGWERK DRUCKFARBEN AG (DE) 2006-06-14 EP disclosed
EP-1118644-A2 Hot melt printing ink Siegwerk Druckfarben GmbH & Co. KG (DE) 2001-07-25 EP disclosed
US-5382683-A 2-aminopropanamide derivatives FISONS CORPORATION (US) 1995-01-17 US disclosed
EP-0326240-B1 2-Amino acetamide derivatives FISONS CORP (US) 1993-10-20 EP disclosed
EP-0279937-B1 2-AMINOACETAMIDE DERIVATIVES FISONS CORPORATION (US) 1991-10-09 EP disclosed
US-5047541-A 2-azacyclocarboxamide derivatives FISONS CORPORATION (US) 1991-09-10 US disclosed
EP-0401253-A1 2-AMINO ACETAMIDE DERIVATIVES FISONS CORPORATION (US) 1990-12-12 EP disclosed
US-4871872-A 2-[(2-aminoacetyl)amino]acetamide derivatives FISONS CORPORATION (US) 1989-10-03 US disclosed
EP-0326240-A1 2-Amino acetamide derivatives FISONS CORPORATION (US) 1989-08-02 EP disclosed
WO-1989006646-A1 2-AMINO ACETAMIDE DERIVATIVES FISONS CORPORATION (US) 1989-07-27 WO disclosed
EP-0279937-A1 2-Aminoacetamide derivatives FISONS CORPORATION (US) 1988-08-31 EP disclosed
EP-0278089-A2 2-Azacyclocarboxamide derivatives FISONS CORPORATION (a Massachusetts corporation) (US) 1988-08-17 EP disclosed