Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695 | 1.00 | KMT2A (0.41) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL11909001 | 0.89 | HTT (0.44) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL11908997 | 0.89 | HTT (0.44) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL11909676 | 0.87 | HTT (0.42) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL6271 | 0.85 | HTT (0.38) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL6574 | 0.85 | HTT (0.38) | KMT2AHTTMEN1MAPT | |
| SCHEMBL6572 | 0.85 | HTT (0.38) | KMT2AHTTMEN1MAPT | |
| SCHEMBL6273 | 0.85 | HTT (0.38) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL6775 | 0.83 | ALDH1A1 (0.48) | KMT2AHTTALDH1A1LMNAMEN1 | |
| SCHEMBL6773 | 0.83 | ALDH1A1 (0.48) | KMT2AHTTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |