Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572 | 1.00 | HTT (0.38) | HTTL3MBTL1TMEM97PRKCQENPP2 | |
| SCHEMBL11909697 | 0.90 | HTT (0.41) | HTTTMEM97PRKCQENPP2GAA | |
| SCHEMBL11909699 | 0.90 | HTT (0.41) | HTTTMEM97PRKCQENPP2GAA | |
| SCHEMBL5697 | 0.85 | KMT2A (0.41) | HTTMEN1KMT2AMAPT | |
| SCHEMBL5695 | 0.85 | KMT2A (0.41) | HTTMEN1KMT2AMAPT | |
| SCHEMBL5643 | 0.84 | SCD (0.42) | HTTTMEM97PRKCQMAPTTDP1 | |
| SCHEMBL5641 | 0.84 | SCD (0.42) | HTTTMEM97PRKCQMAPTTDP1 | |
| SCHEMBL11074 | 0.84 | RBP4 (0.40) | L3MBTL1CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL11909676 | 0.82 | HTT (0.42) | HTTMEN1KMT2AMAPT | |
| SCHEMBL6273 | 0.82 | HTT (0.38) | HTTMEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |