Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 5/20 | 0.64 |
| ▸ | AHR | P35869 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696361 | 0.90 | PLAU (0.65) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL10340578 | 0.88 | KMT2A (0.83) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5695675 | 0.82 | ALDH1A1 (0.70) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5695696 | 0.81 | KMT2A (0.62) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL3925183 | 0.81 | PLG (0.62) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL3010105 | 0.81 | HSD17B1 (0.74) | KMT2AMEN1NPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL3922499 | 0.80 | PLG (0.61) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL14111908 | 0.79 | PLAU (0.76) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL4946900 | 0.79 | KDM4E (0.70) | RAB9AKDM4EALDH1A1LMNATSHR | |
| SCHEMBL26458870 | 0.78 | KMT2A (1.00) | KMT2AMEN1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1652837-A1 | AMINOCARBONYL NAPHTHOL DERIVATIVE, CYANONAPHTHOL DERIVATIVE, AND METHOD FOR PRODUCING THEM | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2006-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | HCCS, CYP8B1, NCAPD3 | KMT2A 3596/4885MEN1 1062/4885NPC1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.