SCHEMBL5697152

SCHEMBL5697152

NC1(N)CCCCC1.O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Pt+2]

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340531 0.94 TSHR (0.33) TSHRCYP2C19MEN1KMT2A
SCHEMBL7861963 0.94 TSHR (0.33) TSHRCYP2C19MEN1KMT2A
SCHEMBL7861964 0.94 TSHR (0.33) TSHRCYP2C19MEN1KMT2A
SCHEMBL10340530 0.94 TSHR (0.33) TSHRCYP2C19MEN1KMT2A
Nitric Acid SCHEMBL5697157 0.87 CA5A (0.38) TSHRCYP2C19
Nitric Acid SCHEMBL5697160 0.84 CA5A (0.40) TSHRCYP2C19
SCHEMBL29738285 0.82
SCHEMBL8672905 0.78 TSHR (0.38) TSHRCYP2C19
SCHEMBL20291779 0.78 TSHR (0.38) TSHRCYP2C19
SCHEMBL261336 0.78 TSHR (0.38) TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975329-B1 LIPID COMPLEXES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES UPJOHN CO (US) 2004-12-08 EP claimed
CN-1096263-C Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2002-12-18 CN claimed
US-6287593-B2 ANTICANCER PHARMACIA & UPJOHN (IT) 2001-09-11 US claimed
CN-120192347-A Compound for treating oxaliplatin resistant tumors, preparation method, composition and application thereof 天津谷堆生物医药科技有限公司 2025-06-24 CN disclosed
WO-2023169433-A1 POLYMER-COATED NANOPARTICLES AND PREPARATION METHOD THEREFOR 晟迪生物医药(苏州)有限公司 2023-09-14 WO disclosed
EP-1705254-A2 Compositions and methods using platinum for nucleic acid labeling Stratagene California (US) 2006-09-27 EP disclosed
EP-1373572-B1 COMPOSITIONS AND METHODS USING PLATINUM COMPOUNDS FOR NUCLEIC ACID LABELING STRATAGENE CALIFORNIA (US) 2006-07-26 EP disclosed
CN-1191067-C Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2005-03-02 CN disclosed
EP-0975329-B1 LIPID COMPLEXES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES UPJOHN CO (US) 2004-12-08 EP disclosed
US-6825330-B2 A PLATINUM COMPOUND COVELENTLY ATTACHED TO A DETACTABLE MARKER VIA A LINKER (LINKER IS A GROUP JOINING NITROGEN TO A FLUOROPHORE, A CHROMOPHORE, A RADIOLABEL, AN ENZYME OR AN AFFINITY TAG) STRATAGENE CALIFORNIA 2004-11-30 US disclosed
CN-1422619-A Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2003-06-11 CN disclosed
CN-1096263-C Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2002-12-18 CN disclosed
US-20020165369-A1 Compositions and methods using platinum compounds for nucleic acid labeling STRATAGENE 2002-11-07 US disclosed
US-6287593-B2 ANTICANCER PHARMACIA & UPJOHN (IT) 2001-09-11 US disclosed
US-20010010822-A1 LIPID COMPLEXES AND LIPOSOMES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES CHERIAN MATHEW (IT) 2001-08-02 US disclosed
CN-1264295-A Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2000-08-23 CN disclosed
EP-0975329-A1 LIPID COMPLEXES AND LIPOSOMES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES PHARMACIA & UPJOHN COMPANY (US) 2000-02-02 EP disclosed
WO-1998033481-A1 LIPID COMPLEXES AND LIPOSOMES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES PHARMACIA & UPJOHN COMPANY (US) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165369-A1 Compositions and methods using platinum compounds for nucleic acid labeling PCNA, CXCR3, APEX1 TSHR 2322/4885CYP2C19 4773/4885MEN1 2246/4885
US-20010010822-A1 LIPID COMPLEXES AND LIPOSOMES OF HIGHLY INSOLUBLE PLATINUM COMPLEXES PHOSPHO1, LIPA, DLD TSHR 4191/4885CYP2C19 3623/4885MEN1 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.