Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765859 | 0.81 | CA2 (0.45) | HSD17B10 | |
| SCHEMBL5423992 | 0.80 | GRM2 (0.38) | CYP4F2CYP4A11ALDH1A1GAAHSD17B10 | |
| SCHEMBL10180044 | 0.80 | LPL (0.47) | LPLLIPGALDH1A1GAAHSD17B10 | |
| SCHEMBL27878821 | 0.74 | IDO1 (0.46) | — | |
| SCHEMBL10180595 | 0.73 | KAT6A (0.48) | ALDH1A1GAAHSD17B10GRM2GRM3 | |
| SCHEMBL5429891 | 0.71 | CYP4F2 (0.51) | LPLLIPGCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL22235687 | 0.71 | LPL (0.61) | LPLLIPG | |
| SCHEMBL6444977 | 0.71 | LPL (0.56) | LPLLIPGPPARGPPARAALDH1A1 | |
| SCHEMBL11426304 | 0.70 | LPL (0.57) | LPLLIPGPPARGPPARAALDH1A1 | |
| SCHEMBL11266570 | 0.70 | LPL (0.57) | LPLLIPGPPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675821-A1 | PHENETANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005044787-A1 | PHENETANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-05-19 | — | — | WO | disclosed |