Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 11/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522324 | 0.91 | HDAC1 (0.69) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL7989152 | 0.85 | HDAC1 (0.77) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| Ammonia Solution, Strong SCHEMBL20302203 | 0.84 | MCL1 (0.69) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL29496337 | 0.83 | GRM4 (0.67) | GRM4HDAC6RAB9ANPC1ALDH1A1 | |
| SCHEMBL29217385 | 0.83 | GRM4 (0.61) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL24298091 | 0.83 | GRM4 (0.67) | GRM4HDAC6RAB9ANPC1ALDH1A1 | |
| SCHEMBL22208965 | 0.83 | HDAC6 (0.59) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL6278943 | 0.81 | GRM4 (1.00) | GRM4HDAC6RAB9ANPC1GAA | |
| SCHEMBL29217384 | 0.81 | ALDH1A1 (0.67) | GRM4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL14360677 | 0.81 | GRM4 (0.51) | GRM4HDAC6HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516041-B1 | USE OF TRANSITION METAL COMPLEXES WITH NITROGEN-CONTAINING POLYDENTATE LIGANDS AS A BLEACHING CATALYST AND BLEACHING AGENT COMPOSITION | DEGUSSA (DE) | 2006-06-28 | — | — | EP | disclosed |
| US-20040053802-A1 | Use of transition metal complexes with nitrogen-containing polydentate ligands as a bleaching catalyst and bleaching agent composition | DEGUSSA AG | 2004-03-18 | — | — | US | disclosed |