Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941015 | 0.89 | REN (0.44) | RENCYP3A4CTSDCTSE | |
| SCHEMBL4930538 | 0.80 | REN (0.45) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5697450 | 0.80 | PRKAB2 (0.34) | — | |
| SCHEMBL4938688 | 0.80 | REN (0.45) | RENCYP3A4CTSDCTSE | |
| SCHEMBL4939031 | 0.79 | REN (0.44) | RENCYP3A4CTSDCTSE | |
| SCHEMBL4937394 | 0.72 | REN (0.46) | RENCYP3A4CTSDCTSE | |
| SCHEMBL4932897 | 0.71 | REN (0.46) | RENCYP3A4CTSDCTSE | |
| SCHEMBL8231660 | 0.71 | REN (0.67) | RENCYP3A4CTSDCTSE | |
| SCHEMBL13232936 | 0.69 | REN (0.65) | RENCYP3A4CTSDCTSE | |
| SCHEMBL5537496 | 0.66 | REN (0.67) | RENCYP3A4CTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673341-A1 | TETRAHYDROPYRIDINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040120-A1 | TETRAHYDROPYRIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-05-06 | — | — | WO | disclosed |