Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010926 | 0.77 | LTA4H (0.50) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL5697485 | 0.74 | LTA4H (0.46) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL10950997 | 0.74 | LTA4H (0.46) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL20708903 | 0.74 | MAOA (0.46) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL6489226 | 0.69 | MEN1 (0.46) | LTA4HTSHRKDM4EKMT2ARAB9A | |
| SCHEMBL1106849 | 0.69 | LMNA (0.44) | LTA4HTSHRPGRKMT2APPARG | |
| SCHEMBL1106848 | 0.69 | TSHR (0.41) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL922635 | 0.69 | CYP2E1 (0.48) | LTA4HTSHRMAOA | |
| SCHEMBL923385 | 0.69 | LTA4H (0.41) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL14657075 | 0.67 | LTA4H (0.86) | LTA4HTSHRNR1H2BAXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |