SCHEMBL5697490

SCHEMBL5697490

Cc1ccc(S(=O)(=O)OCc2ccc(Cl)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.55
ALDH1A1 P00352 3/20 0.55
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
BCHE P06276 1/20 0.54
ACHE P22303 1/20 0.54
CNR2 P34972 4/20 0.51
KMT2A Q03164 5/20 0.50
MEN1 O00255 2/20 0.50
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
HTT P42858 3/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
PKM P14618 1/20 0.46
CNR1 P21554 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697543 0.91 KMT2A (0.56) GAAALDH1A1CA1CA2CA9
SCHEMBL6859827 0.91 CA2 (0.63) GAAALDH1A1CA1CA2CA9
SCHEMBL8052920 0.91 CA2 (0.63) GAAALDH1A1CA1CA2CA9
SCHEMBL7890851 0.85 CA2 (0.56) GAAALDH1A1CA1CA2CA9
SCHEMBL5870520 0.85 CA2 (0.56) GAAALDH1A1CA1CA2CA9
SCHEMBL948326 0.84 CNR2 (0.56) GAAALDH1A1CA1CA2BCHE
SCHEMBL7909564 0.83 CA2 (0.54) ALDH1A1CA1CA2CA9KMT2A
SCHEMBL776679 0.83 CA1 (0.54) GAAALDH1A1CA1CA2CA9
SCHEMBL14266859 0.83 CA2 (0.54) GAAALDH1A1CA1CA2CA9
SCHEMBL19067740 0.83 CA2 (0.54) GAAALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US claimed
US-20170298058-A1 HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE SHIONOGI & CO (JP) 2017-10-19 US disclosed
US-9550763-B2 Heterocyclic ring and carbocyclic derivative SHIONOGI & CO., LTD. (JP) 2017-01-24 US disclosed
US-20160024072-A1 Heterocyclic Ring and Carbocyclic Derivative SHIONOGI & CO., LTD. (JP) 2016-01-28 US disclosed
EP-1000933-B1 TRIFLUORO METHYLTHIOMETHYL BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME IHARA CHEMICAL IND CO (JP) 2006-08-02 EP disclosed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US disclosed
US-20030187178-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2003-10-02 US disclosed
US-6613863-B2 Benzyltrialkylammonium carboxylate isocyanate trimerization catalysts DEGUSSA AG (DE) 2003-09-02 US disclosed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US disclosed
US-6225505-B1 BY REACTING BENZYL HALIDE DERIVATIVE WITH THIOPHOSGENE AND POTASSIUM FLUORIDE IN ACETONITRILE; HIGH YIELD AND PURITY WITHOUT USING OZONE LAYER-DESTROYING SUBSTANCE; USE AS INTERMEDIATE FOR DRUGS AND AGROCHEMICALS IHARA CHEMICAL INDUSTRY CO., LTD (JP) 2001-05-01 US disclosed
EP-1000933-A1 TRIFLUORO METHYLTHIOMETHYL BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME Ihara Chemical Industry Co., Ltd. (JP) 2000-05-17 EP disclosed
US-4339455-A 1-(3-Pyridyl)-2,2,2-trihaloethyl compounds and fungicidal compositions containing the same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1982-07-13 US disclosed
US-4189486-A FUNGICIDES CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1980-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170298058-A1 HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE P2RX3, P2RX7, P2RX2 GAA 4737/4885ALDH1A1 2515/4885CA1 2104/4885
US-20160024072-A1 Heterocyclic Ring and Carbocyclic Derivative P2RX3, P2RX7, P2RX2 GAA 4737/4885ALDH1A1 2515/4885CA1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.