Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 11/20 | 0.57 |
| ▸ | CASP1 | P29466 | 6/20 | 0.57 |
| ▸ | CASP9 | P55211 | 5/20 | 0.57 |
| ▸ | CASP4 | P49662 | 4/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.57 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.57 |
| ▸ | CASP5 | P51878 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 5/20 | 0.55 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697536 | 0.95 | CASP3 (0.61) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL5697538 | 0.88 | CASP3 (0.49) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL3317466 | 0.87 | CASP3 (0.62) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL2038060 | 0.82 | CASP3 (0.63) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL31248472 | 0.81 | CASP3 (0.63) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL2744395 | 0.80 | CASP3 (0.68) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL30541131 | 0.79 | CASP3 (0.61) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL3490826 | 0.78 | CASP3 (0.73) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL23613622 | 0.78 | CASP3 (0.56) | CASP3CASP1CASP9CASP4CASP8 | |
| SCHEMBL20257276 | 0.78 | CASP3 (0.60) | CASP3CASP1CASP9CASP4CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313855-B1 | TRUNCATED BARD1 PROTEIN, AND ITS DIAGNOSTIC AND THERAPEUTIC USES | INST NAT SANTE RECH MED (FR) | 2006-05-31 | — | — | EP | disclosed |