Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.63 |
| ▸ | CASP1 | P29466 | 4/20 | 0.63 |
| ▸ | CASP9 | P55211 | 4/20 | 0.63 |
| ▸ | CASP4 | P49662 | 2/20 | 0.63 |
| ▸ | CASP5 | P51878 | 2/20 | 0.63 |
| ▸ | CASP6 | P55212 | 2/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.63 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | ECE1 | P42892 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541131 | 0.95 | CASP3 (0.61) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL6669609 | 0.93 | CTSB (0.63) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL29362585 | 0.88 | CASP3 (0.76) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL3490826 | 0.87 | CASP3 (0.73) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL23613622 | 0.87 | CASP3 (0.56) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL3317466 | 0.87 | CASP3 (0.62) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL2040978 | 0.86 | CASP3 (0.57) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL2038060 | 0.86 | CASP3 (0.63) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL18114521 | 0.85 | MEN1 (0.59) | CASP3CASP1CASP9CASP4CASP5 | |
| SCHEMBL18114520 | 0.85 | MEN1 (0.59) | CASP3CASP1CASP9CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719370-A1 | COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION | Abrexa Pharmaceuticals, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260076926-A1 | COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION | ABREXA PHARMACEUTICALS, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| WO-2024249415-A1 | COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION | ABREXA PHARMACEUTICALS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260076926-A1 | COMPOUNDS FOR USE IN ORGAN PRESERVATION AND ORGAN TRANSPLANTATION | CASP9, CASP3, CASP10 | CASP3 2/4885CASP1 214/4885CASP9 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.