Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141775 | 0.84 | HRH3 (0.33) | HRH3 | |
| SCHEMBL5048184 | 0.77 | HRH3 (0.50) | HRH3 | |
| SCHEMBL6142247 | 0.76 | PYCR1 (0.45) | — | |
| SCHEMBL20038511 | 0.74 | HRH3 (0.52) | HRH3 | |
| SCHEMBL1126370 | 0.73 | HRH3 (0.50) | HRH3 | |
| SCHEMBL20038509 | 0.73 | HRH3 (0.50) | HRH3 | |
| SCHEMBL7499051 | 0.73 | HRH3 (0.50) | HRH3 | |
| SCHEMBL6141682 | 0.72 | HRH3 (0.56) | HRH3 | |
| SCHEMBL6141789 | 0.70 | BACE1 (0.44) | — | |
| SCHEMBL30786186 | 0.70 | HRH3 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667990-A2 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005027823-A2 | 3-HETEROCYCLYL-INDOLE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) | ASTRAZENECA AB (SE) | 2005-03-31 | — | — | WO | disclosed |