Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5697795

CC(O)C(=O)CC(O)C(=O)O.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
TP53 P04637 1/20 0.48
TET2 Q6N021 6/20 0.44
TET3 O43151 2/20 0.44
TET1 Q8NFU7 1/20 0.44
OR51E2 Q9H255 1/20 0.42
KDM4A O75164 2/20 0.37
KDM4C Q9H3R0 2/20 0.37
KDM2A Q9Y2K7 2/20 0.37
GPR84 Q9NQS5 3/20 0.37
FFAR1 O14842 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410670 0.97 SMN1; SMN2 (0.55) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL2059417 0.93 SMN1; SMN2 (0.50) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL8060390 0.82 SMN1; SMN2 (0.55) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL8071224 0.82 SMN1; SMN2 (0.55) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL8060386 0.82 SMN1; SMN2 (0.55) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL3985265 0.78 SMN1; SMN2 (0.50) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL2935591 0.78 SMN1; SMN2 (0.50) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL9356193 0.78 TP53 (0.40) SMN1; SMN2TP53TET2TET3TET1
Malic Acid SCHEMBL29612 0.77 SMN1; SMN2 (0.79) SMN1; SMN2TP53TET2TET3TET1
SCHEMBL26062129 0.76 SMN1; SMN2 (0.48) SMN1; SMN2TP53TET2TET3TET1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173402-B1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF TATE & LYLE INGREDIENTS (US) 2006-06-21 EP disclosed
EP-1173402-A4 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF STALEY MFG CO A E (US) 2002-08-14 EP disclosed
EP-1173402-A1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF A.E. STALEY MANUFACTURING COMPANY (US) 2002-01-23 EP disclosed
US-6291708-B1 COMBINING AQUEOUS DILUENT, AMMONIUM SALT OF ORGANIC ACID, AND ALCOHOL; HEATING UNDER PRESSURE TO DECOMPOSE THE AMMONIUM SALT OF THE ORGANIC ACID INTO AMMONIA AND FREE ORGANIC ACID WHILE REMOVING AMMONIA; RECOVERING ACID A.E. STALEY MANUFACTURING CO. 2001-09-18 US disclosed
WO-2000064850-A1 PROCESS FOR PRODUCTION OF ORGANIC ACIDS AND ESTERS THEREOF A. E. STALEY MANUFACTURING CO. (US) 2000-11-02 WO disclosed