Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896673 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1NMT2NMT1 | |
| SCHEMBL16615963 | 0.94 | GNAI3 (0.47) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL847122 | 0.93 | GNAI3 (0.44) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL847121 | 0.93 | GNAI3 (0.44) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL30880423 | 0.92 | GNAI3 (0.45) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL8540154 | 0.90 | GNAI3 (0.50) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL8540142 | 0.90 | GNAI3 (0.50) | GNAI3GNAO1GNAI1TERTMMP2 | |
| SCHEMBL31408939 | 0.89 | GSR (0.47) | GNAI3GNAO1GNAI1NMT2NMT1 | |
| SCHEMBL29455851 | 0.89 | GSR (0.47) | GNAI3GNAO1GNAI1NMT2NMT1 | |
| SCHEMBL31676543 | 0.88 | NMT1 (0.45) | NMT2NMT1OPRM1OPRD1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545637-B1 | ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS | JOHNSON & JOHNSON MEDICAL LTD (GB) | 2006-08-02 | — | — | EP | claimed |