SCHEMBL847122

SCHEMBL847122

C[C@H](NC(=O)CNC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GNAI3 P08754 1/20 0.44
▸ GNAO1 P09471 1/20 0.44
▸ GNAI1 P63096 1/20 0.44
▸ NOD1 Q9Y239 2/20 0.43
▸ TERT O14746 1/20 0.43
▸ SLC6A5 Q9Y345 1/20 0.43
▸ FOLH1 Q04609 1/20 0.43
▸ GSR P00390 1/20 0.42
▸ NRP1 O14786 2/20 0.41
▸ OPRM1 P35372 2/20 0.41
▸ OPRD1 P41143 2/20 0.41
▸ CPB2 Q96IY4 3/20 0.40
▸ ERAP2 Q6P179 1/20 0.39
▸ ERAP1 Q9NZ08 1/20 0.39
▸ LNPEP Q9UIQ6 1/20 0.39
▸ MMP2 P08253 1/20 0.39
▸ DPP8 Q6V1X1 1/20 0.39
▸ DPP9 Q86TI2 1/20 0.39
▸ DPP7 Q9UHL4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL847121 1.00 GNAI3 (0.44) GNAI3GNAO1GNAI1NOD1TERT
SCHEMBL30880423 0.99 GNAI3 (0.45) GNAI3GNAO1GNAI1NOD1TERT
SCHEMBL5697801 0.93 GNAI3 (0.42) GNAI3GNAO1GNAI1TERTGSR
SCHEMBL3896673 0.93 GNAI3 (0.42) GNAI3GNAO1GNAI1TERTGSR
SCHEMBL16615963 0.91 GNAI3 (0.47) GNAI3GNAO1GNAI1TERTGSR
SCHEMBL31676590 0.90 FOLH1 (0.51) NOD1TERTSLC6A5FOLH1
SCHEMBL29397210 0.88 GSR (0.50) GNAI3GNAO1GNAI1NOD1SLC6A5
SCHEMBL2887196 0.88 TERT (0.52) GNAI3GNAO1GNAI1NOD1TERT
SCHEMBL2887200 0.88 TERT (0.52) GNAI3GNAO1GNAI1NOD1TERT
SCHEMBL30767178 0.88 PTGS1 (0.43) GNAI3GNAO1GNAI1NOD1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687039-B1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON INC (US) 2009-01-28 — — EP claimed
US-20060269590-A1 Enzyme-sensitive therapeutic wound dressings KINETIC CONCEPTS, INC. 2006-11-30 — — US claimed
EP-1545637-B1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LTD (GB) 2006-08-02 — — EP claimed
EP-1545637-A1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS Johnson & Johnson Medical Ltd. (GB) 2005-06-29 — — EP claimed
WO-2004030711-A1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2004-04-15 — — WO claimed
US-10307505-B2 Wound dressings for the controlled release of therapeutic agents KCI USA, INC. (US) 2019-06-04 — — US disclosed
US-8858987-B2 Wound dressing for the controlled release of therapeutic agents SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2014-10-14 — — US disclosed
EP-1727473-B1 Diagnostic swab and biopsy punch systems ETHICON INC (US) 2012-03-28 — — EP disclosed
US-7601546-B2 Diagnostic test devices SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) 2009-10-13 — — US disclosed
EP-1687039-B1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON INC (US) 2009-01-28 — — EP disclosed
US-20070148214-A1 Wound dressing for the controlled release of therapeutic agents KCI USA, INC. 2007-06-28 — — US disclosed
EP-1727473-A2 DIAGNOSTIC SWAB AND BIOPSY PUNCH SYSTEMS, AND DIAGNOSTIC CAPS FOR USE IN SUCH SYSTEMS Ethicon, Inc. (US) 2006-12-06 — — EP disclosed
US-20060269590-A1 Enzyme-sensitive therapeutic wound dressings KINETIC CONCEPTS, INC. 2006-11-30 — — US disclosed
EP-1687039-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2006-08-09 — — EP disclosed
EP-1545637-B1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LTD (GB) 2006-08-02 — — EP disclosed
WO-2005082254-A2 DIAGNOSTIC SWAB AND BIOPSY PUNCH SYSTEMS, AND DIAGNOSTIC CAPS FOR USE IN SUCH SYSTEMS ETHICON, INC. (US) 2005-09-09 — — WO disclosed
EP-1545637-A1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS Johnson & Johnson Medical Ltd. (GB) 2005-06-29 — — EP disclosed
WO-2005051441-A1 WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC AGENTS ETHICON, INC. (US) 2005-06-09 — — WO disclosed
WO-2004030711-A1 ENZYME-SENSITIVE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2004-04-15 — — WO disclosed
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