Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 5/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenetole SCHEMBL27620099 | 0.88 | LTA4H (0.65) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL203120 | 0.86 | RXRA (0.70) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL30338775 | 0.86 | RXRA (0.70) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL6313369 | 0.86 | BRD4 (0.50) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL398405 | 0.84 | TP53 (0.56) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL11017769 | 0.84 | RXRA (0.51) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL9905755 | 0.84 | MAPT (0.48) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL27995883 | 0.84 | RXRA (0.48) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL9260410 | 0.84 | RXRA (0.66) | RXRARXRBTP53CYP3A4KDM4E | |
| SCHEMBL29426410 | 0.84 | RXRA (0.66) | RXRARXRBTP53CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689906-A1 | METHOD OF PREPARING A METAL-SILICONE RUBBER COMPOSITE | Dow Corning Corporation (US) | 2006-08-16 | — | — | EP | disclosed |
| EP-1680482-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | Dow Corning Corporation (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005056871-A1 | METHOD OF PREPARING A METAL-SILICONE RUBBER COMPOSITE | DOW CORNING CORPORATION (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005044950-A1 | SILICONE COMPOSITION AND POLYMER DISPERSED LIQUID CRYSTAL | DOW CORNING CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |