SCHEMBL5698253

SCHEMBL5698253

N#Cc1cc(Cl)c(C=O)s1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 1/20 0.31
MEN1 O00255 1/20 0.30
PSMD14 O00487 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16742787 0.76 PTPN2 (0.31) PTPN2
SCHEMBL2065462 0.76 PGR (0.36)
SCHEMBL4153107 0.72 ERN1 (0.33)
SCHEMBL1466497 0.72
SCHEMBL25316693 0.68
SCHEMBL8645191 0.68
SCHEMBL18398193 0.68
SCHEMBL27398466 0.68
SCHEMBL8028559 0.68
SCHEMBL27968493 0.68 ALDH1A1 (0.43) MEN1PSMD14LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678259-A2 DISPERSE AZO DYESTUFFS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2006-07-12 EP disclosed
WO-2005040283-A2 DISPERSE AZO DYESTUFFS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-05-06 WO disclosed