Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528684 | 0.79 | CA12 (0.38) | ALDH1A1HSD17B10LMNAGABRA1GABRG2 | |
| SCHEMBL27906710 | 0.78 | LMNA (0.42) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL28278595 | 0.77 | CA12 (0.37) | ALDH1A1HSD17B10LMNAGABRA1GABRG2 | |
| SCHEMBL1668951 | 0.76 | ALDH1A1 (0.34) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL5175430 | 0.76 | CA1 (0.45) | ALDH1A1KDM4EPOLBLMNAGAA | |
| SCHEMBL28816343 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL8562952 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HSD17B10LMNAGABRA1GABRG2 | |
| SCHEMBL2232031 | 0.72 | ALDH1A1 (0.35) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL24020550 | 0.72 | NPC1 (0.36) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL27720962 | 0.72 | NPSR1 (0.37) | ALDH1A1LMNARAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | disclosed |