Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698348 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBHSD17B10LMNA | |
| SCHEMBL27833658 | 0.67 | MAPT (0.36) | ALDH1A1KDM4EPOLBHSD17B10NFKB1 | |
| SCHEMBL1096751 | 0.65 | MTNR1A (0.38) | ALDH1A1KDM4ENFKB1NFKB2RELA | |
| SCHEMBL934637 | 0.64 | MAPT (0.58) | ALDH1A1HSD17B10GAA | |
| SCHEMBL7263716 | 0.64 | PKM (0.58) | ALDH1A1KDM4EPOLBLMNANFKB1 | |
| SCHEMBL2205239 | 0.64 | MTNR1A (0.40) | KDM4EMTNR1AMTNR1BSTING1 | |
| SCHEMBL11238694 | 0.63 | TSHR (0.61) | ALDH1A1KDM4EPOLBMTNR1AMTNR1B | |
| SCHEMBL30591373 | 0.63 | TSHR (0.42) | ALDH1A1HSD17B10LMNAGABRA1GABRG2 | |
| SCHEMBL30822582 | 0.63 | MAPT (0.56) | ALDH1A1HSD17B10GAA | |
| SCHEMBL5236558 | 0.63 | MTNR1A (0.42) | ALDH1A1KDM4ENFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | claimed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | claimed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | ALDH1A1 13/4885KDM4E 1266/4885POLB 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.