Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3055264 | 0.99 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL3064563 | 0.87 | POLB (0.50) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL3556745 | 0.87 | POLB (0.50) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL3064562 | 0.87 | POLB (0.50) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL3067119 | 0.86 | POLB (0.49) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL3067120 | 0.86 | POLB (0.49) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL7218972 | 0.86 | POLB (0.49) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL3059893 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL5698972 | 0.79 | POLB (0.53) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3055260 | 0.78 | LMNA (0.54) | ALDH1A1MAPTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966283-B1 | PHARMACEUTICAL PRODUCTS FOR CURING AND PREVENTING DISEASES RESULTING FROM THE DAMAGING OF THE VASCULAR ENDOTHELIAL CELLS | CYTRX CORP (US) | 2006-06-14 | — | — | EP | disclosed |
| CN-1152871-C | Hydroxylamine derivatives for enhancing the production of molecular chaperones and preparation thereof | �ݰ��п�˹�о���չ��˾ | 2004-06-09 | — | — | CN | disclosed |
| US-6143741-A | TREATING OR PREVENTING ILLNESSES RESULTING FROM DAMAGED ENDOTHELIAL CELLS SUCH AS ATHEROSCLEROSIS, THROMBOSIS, RESTENOSIS, VESSEL SPASM BY ADMINISTERING HYDROXYLAMINE DERIVATIVE | BIOREX Kutato es Fejleszo Rt. (HU) | 2000-11-07 | — | — | US | disclosed |
| EP-0966283-A2 | PHARMACEUTICAL PRODUCTS FOR CURING AND PREVENTING ILLNESSES CONNECTED WITH THE MALFUNCTION OF VASCULAR ENDOTHELIAL CELLS | BIOREX RT. (HU) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998006400-A2 | PHARMACEUTICAL PRODUCTS FOR CURING AND PREVENTING ILLNESSES CONNECTED WITH THE MALFUNCTION OF VASCULAR ENDOTHELIAL CELLS | BIOREX KUTATÓ ÉS FEJLESZTO^' RT. (HU) | 1998-02-19 | — | — | WO | disclosed |