Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487127 | 0.89 | ALOX15 (0.60) | BACE1ALOX15IGF1RHPGDHSD17B10 | |
| SCHEMBL29138367 | 0.85 | IGF1R (0.57) | BACE1ALOX15IGF1RHPGDALDH1A1 | |
| SCHEMBL8409386 | 0.84 | ALOX15 (0.50) | ALOX15IGF1RHPGDALDH1A1HSD17B10 | |
| SCHEMBL4517872 | 0.84 | MEN1 (0.61) | TRPA1BACE1ALOX15HPGDHSD17B10 | |
| SCHEMBL8409251 | 0.82 | IGF1R (0.58) | ALOX15IGF1RALDH1A1HSD17B10TP53 | |
| SCHEMBL1021610 | 0.81 | TRPA1 (0.59) | TRPA1BACE1ALOX15HPGDALDH1A1 | |
| SCHEMBL8683200 | 0.80 | HTT (0.53) | TRPA1ALOX15IGF1RHPGDALDH1A1 | |
| SCHEMBL1426624 | 0.79 | EGFR (0.60) | ALOX15IGF1RHPGDALDH1A1HSD17B10 | |
| SCHEMBL9243499 | 0.79 | BACE1 (0.50) | BACE1ALOX15IGF1RHPGDHSD17B10 | |
| SCHEMBL8702688 | 0.79 | TAAR1 (0.50) | TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101707914-B | Resin composition | TEIJIN LTD | 2012-12-12 | — | — | CN | disclosed |
| CN-101707914-A | Resin composition | TEIJIN LTD | 2010-05-12 | — | — | CN | disclosed |
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |