Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | BCL2 | P10415 | 1/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21307639 | 0.89 | TRPA1 (0.53) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL10886054 | 0.86 | IDH1 (0.70) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL9173452 | 0.86 | IDH1 (0.70) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL51319 | 0.86 | TRPA1 (0.64) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL28392650 | 0.86 | ALOX15 (0.57) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL10787219 | 0.85 | IDH1 (0.63) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL3640977 | 0.84 | TRPA1 (0.48) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL5699002 | 0.84 | TRPA1 (0.52) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL11890536 | 0.83 | ALOX15 (0.62) | MEN1CYP3A4HPGDALOX15KMT2A | |
| SCHEMBL8759223 | 0.82 | IDH1 (0.70) | MEN1CYP3A4HPGDALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993782-A | ALKYL-2-BENZYL-PHENOLS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-11-23 | — | — | US | claimed |
| CN-115243764-B | Heterocyclic derivatives as TRMP antagonists | 奇华顿股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-113574114-B | Resin composition for infrared shielding transparent member and molded article | 帝人株式会社 | 2024-05-28 | — | — | CN | disclosed |
| CN-117957283-A | Resin composition and molded article thereof | 帝人株式会社 | 2024-04-30 | — | — | CN | disclosed |
| CN-117916309-A | Acrylic rubber composition | 株式会社大阪曹达 | 2024-04-19 | — | — | CN | disclosed |
| CN-117813346-A | Latex composition and dip-molded article | 日本瑞翁株式会社 | 2024-04-02 | — | — | CN | disclosed |
| CN-116034116-B | Acrylic rubber excellent in roll processability, strength characteristics and water resistance | 日本瑞翁株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-114026138-B | Acrylic rubber having excellent storage stability | 日本瑞翁株式会社 | 2024-03-19 | — | — | CN | disclosed |
| CN-114051505-B | Acrylic rubber bag excellent in storage stability and processability | 日本瑞翁株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-111989347-B | Method for producing acrylic rubber, and acrylic rubber produced by the method | 日本瑞翁株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-1330705-C | Flame retardant aromatic poly cabonic ester resin composition and finished products | TEIJIN CHEMICAL CO LTD (JP) | 2007-08-08 | — | — | CN | disclosed |
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | ELI LILLY AND COMPANY (US) | 2007-02-15 | — | — | US | disclosed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| CN-1205267-C | Reclaimed resin composition | TEIJIN CHEMICALS LTD (JP) | 2005-06-08 | — | — | CN | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| CN-1408767-A | Flame retardant aromatic poly cabonic ester resin composition and finished products | TEIJIN CHEMICAL CO LTD (JP) | 2003-04-09 | — | — | CN | disclosed |
| CN-1380895-A | Regenerated resin composition | TEIJIN CHEMICALS LTD (JP) | 2002-11-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | PPARA, PPARG, PPARD | MEN1 4753/4885CYP3A4 892/4885HPGD 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.