Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699255 | 0.76 | GAA (0.44) | KDM4EGAA | |
| SCHEMBL1771083 | 0.75 | MEN1 (0.36) | MEN1HTTKMT2A | |
| SCHEMBL28069484 | 0.74 | CCR5 (0.33) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL6650054 | 0.73 | EPHX2 (0.34) | ROCK2KDM4EGAA | |
| SCHEMBL5699142 | 0.72 | MEN1 (0.31) | MEN1HTTKMT2A | |
| SCHEMBL27902978 | 0.72 | HTR3E (0.57) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| Hydrochloric Acid SCHEMBL28168296 | 0.70 | HTR3E (0.56) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL5734957 | 0.69 | HTR3E (0.44) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL23043168 | 0.69 | SCN9A (0.36) | MEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL4103750 | 0.68 | HTR3E (0.40) | HTR3EHTR3BCHRM4CHRM5CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362843-B1 | N-cyclopropyl-2-difluoromethoxy-3-bromoaniline and intermediate used for production thereof | IHARA CHEMICAL IND CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1362843-B1 | N-cyclopropyl-2-difluoromethoxy-3-bromoaniline and intermediate used for production thereof | IHARA CHEMICAL IND CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1031555-B1 | DIFLUOROMETHOXYBENZENE DERIVATIVES AND THEIR USE AS INTERMEDIATES | IHARA CHEMICAL IND CO (JP) | 2005-04-13 | — | — | EP | disclosed |
| EP-1362843-A2 | N-cyclopropyl-2-difluoromethoxy-3-halogenoaniline and intermediate used for production thereof | Ihara Chemical Industry Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6316658-B1 | QUINOLONE CARBOXYLATE CHEMICAL INTERMEDIATES; MICROBIOCIDES, BACTERICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1031555-A1 | N-CYCLOPROPYL-2-DIFLUOROMETHOXY-3-HALOGENOANILINES AND INTERMEDIATES FOR THE PREPARATION THEREOF | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-08-30 | — | — | EP | disclosed |