Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | CCR5 | P51681 | 11/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227167 | 0.91 | LMNA (0.58) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL5628127 | 0.86 | CCR5 (0.63) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL29859226 | 0.86 | CCR5 (0.63) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL29689869 | 0.85 | CCR5 (0.63) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL5700125 | 0.85 | PTGDR2 (0.55) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL30866193 | 0.85 | CCR5 (0.62) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL275887 | 0.85 | CCR5 (0.62) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL5699666 | 0.85 | CCR5 (0.63) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL29690396 | 0.85 | PTGDR2 (0.61) | LMNAALDH1A1MAPTNPC1CYP1A2 | |
| SCHEMBL82269 | 0.85 | PTGDR2 (0.61) | LMNAALDH1A1MAPTNPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687268-A1 | BENZYLETHER AMINE COMPOUNDS USEFUL AS CCR-5 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005047249-A1 | BENZYLETHER AMINE COMPOUNDS USEFUL AS CCR-5 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-05-26 | — | — | WO | disclosed |
| US-20050101644-A1 | Benzylether amine compounds useful as CCR-5 antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101644-A1 | Benzylether amine compounds useful as CCR-5 antagonists | CCR1, CCR3, CCR4 | LMNA 3981/4885ALDH1A1 1080/4885MAPT 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.