Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 9/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.74 |
| ▸ | PGR | P06401 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 8/20 | 0.68 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | BLM | P54132 | 4/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700248 | 1.00 | SHBG (0.74) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL5700529 | 0.91 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL5700534 | 0.91 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL5700292 | 0.85 | HIF1A (0.71) | SHBGNR3C1PGRLMNASERPINA6 | |
| SCHEMBL5700286 | 0.85 | HIF1A (0.71) | SHBGNR3C1PGRLMNASERPINA6 | |
| SCHEMBL5023902 | 0.85 | SHBG (0.81) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 0.85 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 0.85 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18891626 | 0.85 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13965283 | 0.85 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | claimed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | claimed |
| EP-1322660-B1 | 17ALPHA-FLUOROALKYL STEROIDS, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | SCHERING AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| CN-1061983-C | 4-trifluoromethyl-3-ketosteroid compound and synthesizing method thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2001-02-14 | — | — | CN | disclosed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024231-A1 | 17Alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds | CYP17A1, CYP21A2, NR5A1 | SHBG 43/4885NR3C1 106/4885PGR 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.