Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methyltestosterone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR known ✓ | P10275 | 3/20 | 0.72 |
| ▸ | SHBG | P04278 | 9/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 5/20 | 1.00 |
| ▸ | PGR | P06401 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 8/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyltestosterone SCHEMBL29416593 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13575766 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13965283 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL13768123 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4442874 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL6472960 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18657 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL18891626 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL5021655 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Methyltestosterone SCHEMBL4575985 | 1.00 | SHBG (1.00) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110473129-A | A kind of supervision place police service private network application managing and control system based on Android Android and cloud platform | UNIV SHANDONG | 2019-11-19 | — | — | CN | claimed |
| CN-108537071-B | System for realizing non-display secret operation of mobile phone or tablet computer | CHEN HANNING (CN) | 2019-10-29 | — | — | CN | claimed |
| CN-106293750-B | A kind of control method of intelligent display device booting | 北京神州视翰科技有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110011716-A | A kind of earth station | 杭州海康机器人技术有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-105808219-B | A kind of memory headroom distribution method and device | 中国移动通信集团公司 | 2019-06-25 | — | — | CN | claimed |
| CN-109886839-A | A kind of intelligence food delivery system and method | 杭州火小二科技有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-104834623-B | Audio frequency playing method and device | 广州酷狗计算机科技有限公司 | 2019-06-11 | — | — | CN | claimed |
| CN-106227665-B | A kind of equipment starting method and device | 青岛海信移动通信技术股份有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-105302579-B | A kind of occupancy method and apparatus of Installed System Memory | 北京奇虎科技有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109753800-A | Merge the Android malicious application detection method and system of frequent item set and random forests algorithm | 重庆邮电大学 | 2019-05-14 | — | — | CN | claimed |
| CN-203590470-U | Maritime satellite telephone terminal single-mode cabin motherboard | CHENGDU SPACEON TECHNOLOGY CO LTD | 2014-05-07 | — | — | CN | claimed |
| CN-103777958-A | Mobile terminal, and method and device for controlling system function through application program | BEIKE INTERNET SECURITY TECH | 2014-05-07 | — | — | CN | claimed |
| CN-203590472-U | Dual-mode satellite telephone cabin unit motherboard | CHENGDU SPACEON TECHNOLOGY CO LTD | 2014-05-07 | — | — | CN | claimed |
| CN-103677972-A | Method, device and system for presenting virtual desktop metadata | CHINA TELECOM CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103577731-A | Software processing method and device | CHINA MOBILE COMM CORP | 2014-02-12 | — | — | CN | claimed |
| CN-103198201-A | Method and device for controlling game based on simulate keyboard | TENCENT TECH SHENZHEN CO LTD | 2013-07-10 | — | — | CN | claimed |
| CN-103020278-A | Webpage control method and browser | SHENZHEN SKYWORTH DIGITAL TECH | 2013-04-03 | — | — | CN | claimed |
| CN-103019736-A | Language file generation method and device | GUANGDONG OPPO MOBILE TELECOMM | 2013-04-03 | — | — | CN | claimed |
| CN-102929601-A | Application program management method and apparatus | BEIJING XIAOMI TECHNOLOGY CO | 2013-02-13 | — | — | CN | claimed |
| CN-102253833-A | Operation method and device based on application under Android platform | YULONG COMP TELECOMM SCIENT | 2011-11-23 | — | — | CN | claimed |