Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957779 | 0.80 | PTGS2 (0.57) | KMT2AALDH1A1PTGS2CES2CES1 | |
| SCHEMBL743166 | 0.80 | KMT2A (0.72) | KMT2AHSD17B14ALDH1A1PTGS2CES2 | |
| SCHEMBL29485021 | 0.80 | KMT2A (0.72) | KMT2AHSD17B14ALDH1A1PTGS2CES2 | |
| SCHEMBL29373829 | 0.79 | KMT2A (1.00) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL398165 | 0.79 | KMT2A (1.00) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL15408951 | 0.78 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27809961 | 0.78 | KMT2A (0.82) | KMT2AHSD17B14ALDH1A1PTGS2CES2 | |
| SCHEMBL13600090 | 0.78 | KMT2A (0.81) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL2485773 | 0.78 | KMT2A (0.75) | KMT2AHSD17B14ALDH1A1CES2CES1 | |
| SCHEMBL29571462 | 0.78 | KMT2A (0.75) | KMT2AHSD17B14ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270582-B1 | TRIPHENYLPHOSPHINE DERIVATIVES, PALLADIUM OR NICKEL COMPLEXES THEREOF, AND PROCESS FOR PREPARING BIARYL DERIVATIVES | MITSUBISHI RAYON CO (JP) | 2006-08-30 | — | — | EP | disclosed |
| CN-1221534-C | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors | MERCK FROSST CANADA INC (CA) | 2005-10-05 | — | — | CN | disclosed |
| CN-1434801-A | Substited 8-anylquinoline phosphodiesterase-4 inhibitors | MERCK FROSST CANADA INC (CA) | 2003-08-06 | — | — | CN | disclosed |
| EP-1270582-A1 | TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE | Mitsubishi Rayon Co., Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |