Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700233 | 0.82 | TRPV4 (0.48) | HSD11B1 | |
| SCHEMBL6928310 | 0.79 | HSD11B1 (0.44) | HSD11B1ALDH1A1PGRGAATSHR | |
| SCHEMBL8788731 | 0.77 | HTT (0.43) | HSD11B1ALDH1A1PGRHTTGAA | |
| SCHEMBL1124590 | 0.72 | HSD11B1 (0.40) | HSD11B1ALDH1A1PGRHTTGAA | |
| SCHEMBL395266 | 0.72 | HSD11B1 (0.51) | HSD11B1ALDH1A1PGRGAATSHR | |
| SCHEMBL30720453 | 0.72 | HSD11B1 (0.51) | HSD11B1ALDH1A1PGRGAATSHR | |
| SCHEMBL5607508 | 0.72 | HTR6 (0.48) | ALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL248010 | 0.71 | HSD11B1 (0.59) | HSD11B1ALDH1A1PGRGAATSHR | |
| SCHEMBL30697126 | 0.71 | HSD11B1 (0.59) | HSD11B1ALDH1A1PGRGAATSHR | |
| SCHEMBL2123876 | 0.71 | HSD11B1 (0.59) | HSD11B1ALDH1A1PGRGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1146037-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS | NIPPON SODA CO (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6410749-B1 | REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND | NIPPON SODA CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1146037-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS | NIPPON SODA CO., LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |