Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.73 |
| ▸ | PGR | P06401 | 5/20 | 0.73 |
| ▸ | AR | P10275 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728176 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL3223453 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL111403 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4654367 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL5495390 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4156578 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4728177 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4826587 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL409204 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4165771 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684721-A2 | AEROSOL FORMULATIONS COMPRISING A CARBOXYLIC ACID SURFACTANT | GLAXO GROUP LIMITED (GB) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005065650-A2 | AEROSOL FORMULATIONS COMPRISING A CARBOXYLIC ACID SURFACTANT | GLAXO GROUP LIMITED (GB) | 2005-07-21 | — | — | WO | disclosed |
| EP-1471895-A1 | FORMULATION FOR INHALATION COMPRISING A GLUCOCORTICOID AND A BETA 2-ADRENORECEPTOR AGONIST | GLAXO GROUP LIMITED (GB) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066033-A1 | FORMULATION FOR INHALATION COMPRISING A GLUCOCORTICOID AND A BETA 2-ADRENORECEPTOR AGONIST | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | disclosed |