Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.73 |
| ▸ | PGR | P06401 | 5/20 | 0.73 |
| ▸ | AR | P10275 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728176 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL3223453 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL5700595 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4654367 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL5495390 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4156578 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4728177 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4826587 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL409204 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4165771 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 892 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216353-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-07-04 | — | — | US | claimed |
| US-20210315873-A1 | METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-10-14 | — | — | US | claimed |
| US-8752543-B2 | Fluid dispensing device | GLAXO GROUP LIMITED (GB) | 2014-06-17 | — | — | US | claimed |
| US-8338424-B2 | Guanidine-containing compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2012-12-25 | — | — | US | claimed |
| US-20120219509-A1 | GUANIDINE-CONTAINING COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2012-08-30 | — | — | US | claimed |
| EP-1699512-B1 | A FLUID DISPENSING DEVICE | GLAXO GROUP LTD (GB) | 2012-06-20 | — | — | EP | claimed |
| EP-1471895-B2 | FORMULATION FOR INHALATION COMPRISING A GLUCOCORTICOID AND A BETA 2-ADRENORECEPTOR AGONIST | GLAXO GROUP LTD (GB) | 2012-03-14 | — | — | EP | claimed |
| EP-1706371-B1 | ARYL ANILINE DERIVATIVES AS BETA2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2011-04-06 | — | — | EP | claimed |
| US-7846973-B2 | Chemical process and new crystalline form | THERAVANCE, INC. (US) | 2010-12-07 | — | — | US | claimed |
| US-7798368-B2 | Fluid dispensing device | GLAXO GROUP LIMITED (GB) | 2010-09-21 | — | — | US | claimed |
| WO-2004012799-A2 | A FLUID DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2004-02-12 | — | — | WO | claimed |
| WO-2004011070-A1 | MEDICAMENT DISPENSER | GLAXO GROUP LIMITED (GB) | 2004-02-05 | — | — | WO | claimed |
| US-20030229058-A1 | Aryl aniline beta2 adrenergic receptor agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2003-12-11 | — | — | US | claimed |
| WO-2003095006-A2 | A FLUID DISPENSING DEVICE | GLAXO GROUP LIMITED (GB) | 2003-11-20 | — | — | WO | claimed |
| WO-2003066033-A1 | FORMULATION FOR INHALATION COMPRISING A GLUCOCORTICOID AND A BETA 2-ADRENORECEPTOR AGONIST | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | claimed |
| US-20030092690-A1 | Novel anti-inflammatory androstane derivatives | GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) | 2003-05-15 | — | — | US | claimed |
| EP-1305330-A1 | 17.BETA.-CARBOTHIOATE 17.ALPHA.-ARYLCARBONYLOXYLOXY ANDROSTANE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2003-05-02 | — | — | EP | claimed |
| US-6537983-B1 | An ene or diene steroid inhaler for treating asthma, once-per-day dosing | SMITHKLINE BEECHAM CORPORATION | 2003-03-25 | — | — | US | claimed |
| US-20030045512-A1 | NOVEL ANTI-INFLAMMATORY ANDROSTANE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) | 2003-03-06 | — | — | US | claimed |
| WO-2002012266-A1 | 17.BETA.-CARBOTHIOATE 17.ALPHA.-ARYLCARBONYLOXYLOXY ANDROSTANE DERIVATIVE AS ANTI-INFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 2002-02-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092690-A1 | Novel anti-inflammatory androstane derivatives | ADRB1, ADRB2, ADRB3 | NR3C1 7/4885PGR 400/4885AR 34/4885 |
| US-20030229058-A1 | Aryl aniline beta2 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | NR3C1 226/4885PGR 992/4885AR 101/4885 |
| US-20120219509-A1 | GUANIDINE-CONTAINING COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | CHRM3, CHRM5, CHRM1 | NR3C1 509/4885PGR 1127/4885AR 864/4885 |
| US-20030045512-A1 | NOVEL ANTI-INFLAMMATORY ANDROSTANE DERIVATIVES | ADRB1, NR3C2, NR3C1 | NR3C1 3/4885PGR 473/4885AR 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.