Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.73 |
| ▸ | PGR | P06401 | 5/20 | 0.73 |
| ▸ | AR | P10275 | 5/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223453 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL5700595 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL111403 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4654367 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL5495390 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4156578 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4728177 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4826587 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL409204 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL4165771 | 1.00 | NR3C1 (0.73) | NR3C1PGRARCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439393-B2 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2008-10-21 | — | — | US | claimed |
| US-20080003290-A1 | Phenethanolamine Derivatives for Treatment of Respiratory Diseases | GLAXO GROUP LIMITED (GB) | 2008-01-03 | — | — | US | claimed |
| CN-106432246-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| WO-2008024728-A2 | AEROSOL INHALER WITH AIRFLOW INTRODUCED INTO MOUTHPIECE | GLAXO GROUP LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| EP-1848444-A1 | PROCESSES FOR MAKING LACTOSE UTILIZING PRE-CLASSIFICATION TECHNIQUES AND PHARMACEUTICAL FORMULATIONS FORMED THEREFROM | GLAXO GROUP LIMITED (GB) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006086270-A1 | PROCESSES FOR MAKING LACTOSE UTILIZING PRE-CLASSIFICATION TECHNIQUES AND PHARMACEUTICAL FORMULATIONS FORMED THEREFROM | GLAXO GROUP LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080003290-A1 | Phenethanolamine Derivatives for Treatment of Respiratory Diseases | PHOSPHO1, PNMT, PEBP1 | NR3C1 2819/4885PGR 2859/4885AR 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.