Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 12/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700886 | 0.79 | MEN1 (0.48) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5700880 | 0.79 | MEN1 (0.48) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5700932 | 0.78 | MEN1 (0.60) | TACR3MEN1KMT2APOLBROCK2 | |
| SCHEMBL5700925 | 0.78 | MEN1 (0.60) | TACR3MEN1KMT2APOLBROCK2 | |
| SCHEMBL5700835 | 0.77 | SGPL1 (0.49) | TACR3MEN1KMT2A | |
| SCHEMBL5700842 | 0.77 | SGPL1 (0.49) | TACR3MEN1KMT2A | |
| SCHEMBL5700869 | 0.76 | KMT2A (0.44) | TACR3MEN1KMT2APOLB | |
| SCHEMBL5700864 | 0.76 | KMT2A (0.44) | TACR3MEN1KMT2APOLB | |
| SCHEMBL5701021 | 0.75 | MAPT (0.50) | MEN1KMT2APOLB | |
| SCHEMBL5701028 | 0.75 | MAPT (0.50) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |