Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563562 | 0.74 | KDM5A (0.48) | KDM4EKDM4CKDM5AKDM5BALDH1A1 | |
| SCHEMBL21297851 | 0.73 | L3MBTL1 (0.42) | KDM4EL3MBTL1MAOBMAPTFEN1 | |
| Methane SCHEMBL27733031 | 0.72 | KDM5A (0.47) | KDM4EKDM4CKDM5AKDM5BALDH1A1 | |
| SCHEMBL12439934 | 0.72 | L3MBTL1 (0.36) | KDM4EKDM4CL3MBTL1KDM5AKDM5B | |
| Ammonia Solution, Strong SCHEMBL28358675 | 0.72 | L3MBTL1 (0.41) | KDM4EL3MBTL1MAOBMAPTFEN1 | |
| SCHEMBL16517407 | 0.70 | NPC1 (0.38) | KDM4EKDM4CL3MBTL1KDM6BKDM6A | |
| SCHEMBL16516797 | 0.70 | PDE4A (0.44) | KDM4EALKBH5MEN1KMT2AALDH1A1 | |
| SCHEMBL18074311 | 0.70 | CYP1A2 (0.34) | KDM4CKDM5ADHODHKDM5BMAOB | |
| SCHEMBL3367559 | 0.70 | PRNP (0.38) | KDM4EL3MBTL1KDM4AEGLN1TDP1 | |
| SCHEMBL4550466 | 0.70 | KDM4C (0.52) | KDM4EKDM4CL3MBTL1KDM6BKDM6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |