SCHEMBL5701536

SCHEMBL5701536

C=Cc1ccc([Si](OC(C)C)(OC(C)C)OC(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
ALDH1A3 P47895 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6436939 0.91 ALDH1A1 (0.39) ALDH1A1TSHRHDAC8TAS1R3TAS1R1
SCHEMBL30289898 0.88 ALDH1A1 (0.32) ALDH1A1
SCHEMBL29362223 0.83 CYP3A4 (0.35) ALDH1A1TSHRCHRNB2CHRNA7TRPA1
SCHEMBL426114 0.82
SCHEMBL6436935 0.82 ALDH1A1 (0.42) ALDH1A1TSHRHDAC8TAS1R3TAS1R1
SCHEMBL3761540 0.82 ALDH1A1 (0.42) ALDH1A1TSHRHDAC8TAS1R3TAS1R1
SCHEMBL5702032 0.78 TP53 (0.44) ALDH1A1TSHRHDAC8TRPA1TDP1
SCHEMBL28619812 0.78 ALDH1A1 (0.38) ALDH1A1TSHRHDAC8TAS1R3TAS1R1
SCHEMBL29434580 0.78 TP53 (0.44) ALDH1A1TSHRHDAC8TRPA1TDP1
SCHEMBL27813923 0.77 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493542-B Conjugated diene polymer, process for producing the same, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2023-09-22 CN claimed
CN-112979876-B Branched conjugated diene polymer and method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2023-09-08 CN claimed
CN-113372630-B Conjugated diene polymer composition and tire 旭化成株式会社 2023-05-26 CN claimed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
US-20240425702-A1 Block Copolymer, Asphalt Composition, and Modified Asphalt Mixture ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed
EP-0823450-B1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO (JP) 2004-11-24 EP disclosed
EP-0696621-B1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO (JP) 2000-10-11 EP disclosed
US-5939471-A COLLOIDAL SILICA DISPERSED IN RESIN MITSUBISHI RAYON CO., LTD. (JP) 1999-08-17 US disclosed
EP-0823450-A1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO., LTD. (JP) 1998-02-11 EP disclosed
US-5695851-A CROSSLINKABLE, POLYMERIZABLE COMPOSITION CONTAINING (METH)ACRYLOYLOXY GROUPS, SILICA WHOSE SURFACE HAS BEEN MODIFIED WITH AN ORGANOSILANE-CONTAINING COMPOUND, AND A HIGH ENERGY RADIATION POLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1997-12-09 US disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 ALDH1A1 2948/4885TSHR 159/4885HDAC8 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.