SCHEMBL5702146

SCHEMBL5702146

CCNC(=O)Oc1cccc(O)c1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.59
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13386686 0.86 CYP3A4 (0.58) CYP3A4ESR1ESR2
SCHEMBL13386797 0.84 CYP3A4 (0.56) CYP3A4ESR1ESR2
SCHEMBL5702187 0.83 LMNA (0.59) CYP3A4
SCHEMBL5702214 0.83 MTNR1B (0.56)
SCHEMBL5702114 0.82 FAAH (0.62)
SCHEMBL7606599 0.82 NPC1 (0.45)
SCHEMBL6228259 0.82 KMT2A (0.59)
SCHEMBL659111 0.82 CYP3A4 (0.50) CYP3A4ACHE
SCHEMBL9126647 0.82 ESR1 (0.53) CYP3A4ESR1ESR2
SCHEMBL10971933 0.81 CYP3A4 (0.65) CYP3A4ESR1ESR2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP claimed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO claimed
CN-113474156-B Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2022-04-29 CN disclosed
CN-113474156-A Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2021-10-01 CN disclosed
CN-112010763-A Preparation method of m-aminophenol 浙江理工大学 2020-12-01 CN disclosed
CN-105263929-B 3-Pyrimidin-4-yl-oxazolidin-2-one compounds as mutant IDH inhibitors 诺华股份有限公司 2018-08-28 CN disclosed
CN-105263929-A 3-Pyrimidin-4-yl-oxazolidin-2-one compounds as mutant IDH inhibitors NOVARTIS AG 2016-01-20 CN disclosed
CN-102574855-A Pteridines and their use as pesticides DOW AGROSCIENCES LLC 2012-07-11 CN disclosed
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP disclosed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO disclosed
EP-1123918-B1 AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME TAKEDA PHARMACEUTICAL (JP) 2005-03-09 EP disclosed
EP-1123918-A1 AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME Takeda Chemical Industries, Ltd. (JP) 2001-08-16 EP disclosed