SCHEMBL28091167

SCHEMBL28091167

CCCN(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.46
ESR2 Q92731 1/20 0.46
LTB4R2 Q9NPC1 2/20 0.46
TP53 P04637 1/20 0.44
ESRRG P62508 2/20 0.42
HSD17B3 P37058 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
TSHR P16473 1/20 0.41
MLYCD O95822 2/20 0.41
TRPM8 Q7Z2W7 1/20 0.39
NPC1 O15118 1/20 0.38
JAK2 O60674 1/20 0.38
RAB9A P51151 1/20 0.38
PAX8 Q06710 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164621 0.84 TP53 (0.61) TP53ALDH1A1GLATSHRTRPM8
SCHEMBL5702149 0.84 ALDH1A1 (0.53) ESR1ESR2LTB4R2TP53ESRRG
SCHEMBL16416338 0.83 PDK1 (0.45) ESR1ESR2LTB4R2TP53ALDH1A1
SCHEMBL11490011 0.83 CYP3A4 (0.44) TP53ALDH1A1GLATSHRMLYCD
SCHEMBL5218475 0.83 TP53 (0.43) TP53ALDH1A1GLATSHRMLYCD
SCHEMBL7197819 0.82 LTB4R2 (0.54) ESR1LTB4R2TP53HSD17B3ALDH1A1
SCHEMBL7195860 0.82 LTB4R2 (0.54) ESR1LTB4R2TP53HSD17B3ALDH1A1
SCHEMBL28736041 0.81 TP53 (0.50) LTB4R2TP53ALDH1A1GLATSHR
SCHEMBL28014992 0.80 TP53 (0.41) LTB4R2TP53ALDH1A1GLATSHR
SCHEMBL11463976 0.80 NOX1 (0.41) TP53ALDH1A1GLATSHRMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105802610-B Fluorine ion fluorescent probe and application 中国科学院理化技术研究所 2018-05-04 CN disclosed
CN-105802610-A Fluorine ion fluorescent probe and application 中国科学院理化技术研究所 2016-07-27 CN disclosed