Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13447587 | 0.81 | SMN1; SMN2 (0.49) | TDP1SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL7779084 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL13221992 | 0.77 | ESR1 (0.44) | CYP1A2MAPTTDP1L3MBTL1ALDH1A1 | |
| Formic Acid Phenyl Ester SCHEMBL2662 | 0.76 | — | — | |
| SCHEMBL21118545 | 0.75 | LTA4H (0.55) | TSHRMEN1KMT2A | |
| SCHEMBL15628358 | 0.75 | KIF11 (0.43) | CYP1A2MAPTSMN1; SMN2ALDH1A1KIF11 | |
| Formic Acid Phenyl Ester SCHEMBL11036284 | 0.74 | TSHR (0.39) | TSHRTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL5703232 | 0.74 | TSHR (0.35) | TSHRCYP1A2GAALMNAKMT2A | |
| SCHEMBL21538651 | 0.74 | ESR1 (0.42) | MAPTTDP1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9887145 | 0.74 | ESR1 (0.65) | TSHRCYP1A2MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | Epoch Biosciences, Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005043127-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |