Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221217 | 0.76 | CA1 (0.46) | TSHRGAAKMT2A | |
| SCHEMBL5703237 | 0.74 | TSHR (0.38) | TSHRCYP1A2LMNAGAAKMT2A | |
| SCHEMBL1996546 | 0.73 | PPARG (0.41) | LMNAGAA | |
| SCHEMBL18415682 | 0.73 | ALDH1A1 (0.45) | TSHRCYP1A2GAA | |
| SCHEMBL28774590 | 0.72 | TDP1 (0.44) | TSHRCYP1A2GAA | |
| SCHEMBL221587 | 0.72 | CA1 (0.46) | TSHRGAAKMT2A | |
| SCHEMBL7865518 | 0.71 | ALDH1A1 (0.44) | CYP1A2GAA | |
| SCHEMBL9881101 | 0.71 | ALDH1A1 (0.42) | TSHRCYP1A2LMNAGAAKMT2A | |
| SCHEMBL2094131 | 0.70 | RXRA (0.33) | — | |
| SCHEMBL14746123 | 0.69 | CPA3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | Epoch Biosciences, Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005043127-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |